Shaping Innovative Products for Sustainable Tissue Engineering Strategies
The Project
Welcome to SHIFT, the cutting-edge research and mobility project funded by the European Union under the MSCA-RISE instrument, G.A. 101008041. As the successor to the MSCA-RISE REMIX project, SHIFT continues to push the boundaries of tissue engineering and regenerative medicine.
The SHIFT project focuses on developing sustainable solutions for tissue engineering, particularly in regenerative medicine. It builds on natural-based materials research, such as silk and collagen, aiming to create scalable, eco-friendly medical prototypes for treating conditions like chronic wounds and bone defects. The project collaborates with international universities and emphasizes green chemistry, regulatory compliance, and training early-stage researchers to bridge academia and industry.
Raw materials purification protocols design
Upscaling advanced manufacturing technologies
Translational platforms for product development
Communication and dissemination
Our Mission
While REMIX explored the potential of natural materials like silk proteins, collagen, keratin, and marine-derived polymers for tissue engineering, SHIFT aims to elevate this research by designing innovative, scalable constructs that promote angiogenesis. Our goal is to develop treatments for chronic conditions such as large bone and cartilage defects and chronic wounds (e.g., diabetic ulcers). Prototypes will be designed with scalability, cost-efficiency, and regulatory compliance in mind.
Our Strategies
To achieve our mission, we will employ multiple strategies:
- Regulatory Framework Pre-assessment: Close collaboration with the industry to navigate TERM product regulations.
- Fabrication Standards: Adhering to GMP and ISO quality management system requirements.
- Standardized Protocols: Purifying raw materials from textile and food industry waste to produce medical-grade prototypes, opening new avenues for industrial waste reuse.
- Green Chemistry: Applying eco-friendly principles to minimize environmental impact.
Training and Development
We are committed to nurturing the next generation of researchers through an extensive training program. Early Stage Researchers (ESRs) will benefit from summer schools and online seminars covering TERM, technology, and product development regulations. Special emphasis will be placed on product development, spin-offs, and venture capital to equip junior researchers with the skills to transfer innovations from academia to industry successfully.
Join us at SHIFT as we forge new paths in tissue engineering, creating sustainable and innovative solutions for tomorrow’s medical challenges.